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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Donation return time at fixed and mobile donation sites.

Patricia M Carey1, Patrick M High, Karen S Schlumpf

  • 1University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267-0055, USA. patricia.carey@uc.edu

Transfusion
|July 13, 2011
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Summary

Fixed and mobile blood donation environments impact donor return times. Fixed locations and alternating sites are associated with shorter return intervals for whole blood, plateletpheresis, and double red blood cell donations.

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Area of Science:

  • Blood Transfusion Medicine
  • Public Health
  • Epidemiology

Background:

  • The blood donation environment, whether fixed or mobile, may influence donor return frequency.
  • Understanding these environmental effects is crucial for optimizing blood collection strategies.

Purpose of the Study:

  • To investigate how blood donation environments (fixed vs. mobile) affect donor return intervals.
  • To analyze the impact of different donation types (whole blood, apheresis) and sponsor types on donation return time.

Main Methods:

  • Analysis of data from six US blood centers (2006-2009) within the Retrovirus Epidemiology Donor Study-II (REDS-II).
  • Descriptive statistics stratified by donation type (whole blood, plateletpheresis, double red blood cell) for fixed and mobile locations.
  • Survival analysis to estimate median return times, controlling for demographics, blood center, and mandatory recovery periods.

Main Results:

  • Whole blood donations predominantly occurred at mobile sites (67.9%), while plateletpheresis donations were mainly at fixed sites (97.4%).
  • Shortest median return times were observed at fixed or alternating fixed/mobile sites: 36 days for whole blood, 30 days for double red blood cells, and 23 days for plateletpheresis.
  • Community-based mobile locations showed the longest median return time for plateletpheresis (693 days).

Conclusions:

  • Donors exhibiting the shortest inter-donation intervals were associated with fixed donation sites or those alternating between fixed and mobile locations.
  • These associations persisted even after accounting for mandatory recovery times specific to each donation procedure.