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Assessment of atrial conduction time in patients with coronary artery ectasia

Cihan Sengul1, Cihan Cevik, Olcay Ozveren

  • 1Division of Cardiology, Camlica Alman Hospital, Istanbul, Turkey.

Pacing and Clinical Electrophysiology : PACE
|July 13, 2011
PubMed

Insights

Patients with coronary artery ectasia (CAE) exhibit prolonged P-wave dispersion and interatrial conduction delay. These findings suggest potential atrial conduction abnormalities in individuals with CAE.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Diagnostic Imaging

Background:

  • Coronary artery ectasia (CAE) is linked to sympathetic overactivity, inflammation, and oxidative stress.
  • These factors are also associated with arrhythmias like atrial fibrillation.
  • Atrial conduction abnormalities in CAE patients remain understudied, particularly regarding electromechanical delay.

Purpose of the Study:

  • To investigate atrial electromechanical delay in patients with coronary artery ectasia (CAE).
  • To compare atrial conduction parameters in CAE patients versus those with nonobstructive coronary artery disease (NO-CAD) and healthy controls.

Main Methods:

  • Compared electrocardiographic P-wave measurements and echocardiographic atrial electromechanical coupling (AEC) parameters.
  • Assessed interatrial conduction delay in 90 patients: 30 with CAE, 30 with NO-CAD, and 30 controls.
  • Utilized tissue Doppler echocardiography to evaluate atrial electromechanical delay.

Main Results:

  • Patients with CAE showed significantly increased P-wave dispersion and interatrial conduction delay compared to NO-CAD and control groups.
  • Higher mitral, septal, and tricuspid AEC were observed in the CAE group.
  • Interatrial conduction delay and P-wave dispersion correlated positively with the number of ectatic segments.

Conclusions:

  • P-wave dispersion and interatrial conduction delay are prolonged in patients with CAE.
  • These findings highlight potential atrial conduction abnormalities in CAE.
  • The number of ectatic segments independently predicts interatrial conduction delay.
Abstract

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