Related Experiment Video
Updated: May 31, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
[Anticoagulation and atrial fibrillation]
Sebastián Prieto1, Pablo Young, José M Ceresetto
1Servicio de Hematología, Hospital Británico de Buenos Aires, Argentina.
Insights
Atrial fibrillation (AF), a common heart rhythm disorder, significantly raises stroke risk. Guidelines help manage AF, balancing anticoagulation benefits against bleeding risks for better patient outcomes.
Area of Science:
- Cardiology
- Geriatrics
Context:
- Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults, with incidence increasing significantly with age.
- AF elevates stroke risk fivefold and is responsible for 15% of all strokes.
- Management strategies include preventing thromboembolic events, controlling heart rate, and rhythm control.
Purpose:
- To review current understanding and management guidelines for atrial fibrillation.
- To provide a framework for optimizing treatment in a clinically heterogeneous patient population.
Summary:
- Anticoagulation is crucial for preventing thromboembolic events in AF patients, with benefits outweighing bleeding risks, even in the elderly.
- Established guidelines from major cardiology and chest physician societies aid in decision-making for AF management.
- These directives aim to standardize and improve care for patients with atrial fibrillation.
Impact:
- Improved clinical decision-making for atrial fibrillation management.
- Enhanced prevention of stroke and thromboembolic complications in elderly and high-risk populations.
- Facilitation of better patient outcomes through evidence-based treatment protocols.
Abstract:
Atrial fibrillation is the most frequent cardiac arrhythmia in adults. Its frequency increases with age, being its incidence 1.5% in individuals 50 to 59 years old and 8-10% from 80 to 89 years. Atrial fibrillation increases 5 fold the risk of suffering stroke and actually causes 15% of all strokes. Its management focuses primary in the prevention of thromboembolic phenomena, heart rate and rhythm control. Anticoagulation, when indicated, has demonstrated to be the main tool in the prevention of these thromboembolic events. Although the bleeding complication is frequent in this population and increases with age, anticoagulation benefits are greater than the risks of bleeding. Due to the clinically heterogeneous nature of this arrythmia and the difficulty of establishing appropriate treatment for each particular case, the American College of Cardiology, the American Heart Association, European Society of Cardiology and American College of Chest Physicians have established guidelines to improve the management of these patients. The review of this condition and the proposed directives can notably facilitate and improve the management of the patients with atrial fibrillation.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Venous Thrombosis III: Interprofessional Care
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Dysrhythmias VI: Management of Dysrhythmias

