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Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses
1Biological Science Institute, R&D Center, Nippon Zeon Co. Ltd, Kawasaki, Japan.
Vaccine
|October 1, 1990
Abstract:
The haemagglutinin-neuraminidase gene of Newcastle disease virus was inserted into a non-essential region of the fowlpox virus genome and expressed under control of the vaccinia virus 7.5 kDa polypeptide gene promoter. Immunization with the recombinant fowlpox virus elicited protective immunity in chickens against both virulent Newcastle disease and fowlpox virus infection.