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Protection against lethal equine herpes virus type 1 (subtype 1) infection in hamsters by immune stimulating
R F Cook1, T O'Neill, E Strachan
1Department of Infectious Diseases, Animal Health Trust, Newmarket, Suffolk, UK.
Vaccine
|October 1, 1990
Abstract:
An experimental ISCOM vaccine has been prepared from gradient purified equine herpes virus type 1 (EHV-1). Radiolabelling studies demonstrated that this vaccine contained all the major viral glycoproteins in relative amounts similar to those found in non-detergent disrupted viral preparations. This EHV-1 ISCOM vaccine generated fully protective responses in hamsters challenged with an otherwise lethal dose of the hamster-adapted EHV-1 strain RACH.