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Prediction of pneumonia in a pediatric emergency department
Mark I Neuman1, Michael C Monuteaux, Kevin J Scully
1Division of Emergency Medicine, 300 Longwood Ave, Boston, MA 02115. mark.neuman@childrens.harvard.edu.
Insights
Clinical history and physical exam findings can identify children at low risk for radiographic pneumonia, potentially reducing unnecessary chest X-rays in the emergency department.
Area of Science:
- Pediatric Emergency Medicine
- Radiology
- Clinical Decision Making
Background:
- Pneumonia is a common diagnosis in children presenting to emergency departments.
- Chest radiography is frequently used but may lead to overdiagnosis and unnecessary radiation exposure.
Purpose of the Study:
- To identify historical and physical examination findings associated with radiographic pneumonia in children.
- To develop a clinical decision rule to guide the use of chest radiography for suspected pediatric pneumonia.
Main Methods:
- Prospective cohort study of 2574 children under 21 with suspected pneumonia.
- Multivariate logistic regression and recursive partitioning analysis were used.
- Pneumonia defined by attending radiologist interpretation of chest radiographs.
Main Results:
- Radiographic pneumonia was present in 16% of patients.
- Key predictors included chest pain, focal rales, fever duration, and triage oximetry.
- Hypoxia (oxygen saturation ≤92%) was the strongest predictor (OR: 3.6).
- A subgroup with specific negative findings had a low pneumonia rate (7.6% radiographic, 2.9% definite).
Conclusions:
- Historical and physical examination findings are valuable for risk stratification.
- These findings can help identify children at low risk for radiographic pneumonia, potentially reducing the need for imaging.
Objective:
To study the association between historical and physical examination findings and radiographic pneumonia in children who present with suspicion for pneumonia in the emergency department, and to develop a clinical decision rule for the use of chest radiography.
Methods:
We conducted a prospective cohort study in an urban pediatric emergency department of patients younger than 21 who had a chest radiograph performed for suspicion of pneumonia (n = 2574). Pneumonia was categorized into 2 groups on the basis of an attending radiologist interpretation of the chest radiograph: radiographic pneumonia (includes definite and equivocal cases of pneumonia) and definite pneumonia. We estimated a multivariate logistic regression model with pneumonia status as the dependent variable and the historical and physical examination findings as the independent variables. We also performed a recursive partitioning analysis.
Results:
Sixteen percent of patients had radiographic pneumonia. History of chest pain, focal rales, duration of fever, and oximetry levels at triage were significant predictors of pneumonia. The presence of tachypnea, retractions, and grunting were not associated with pneumonia. Hypoxia (oxygen saturation ≤92%) was the strongest predictor of pneumonia (odds ratio: 3.6 [95% confidence interval (CI): 2.0-6.8]). Recursive partitioning analysis revealed that among subjects with O₂ saturation >92%, no history of fever, no focal decreased breath sounds, and no focal rales, the rate of radiographic pneumonia was 7.6% (95% CI: 5.3-10.0) and definite pneumonia was 2.9% (95% CI: 1.4-4.4).
Conclusion:
Historical and physical examination findings can be used to risk stratify children for risk of radiographic pneumonia.
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