Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extended hepatectomy for hepatocellular carcinoma.

S al-Hadeedi1, T K Choi, J Wong

  • 1Department of Surgery, University of Hong Kong, Queen Mary Hospital.

The British Journal of Surgery
|November 1, 1990
PubMed
Summary

Extended hepatectomy offers comparable outcomes to lesser liver resections for hepatocellular carcinoma. This procedure is a viable option for large liver tumors, presenting an alternative to liver transplantation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of Neisseria cinerea with ocular infections in paediatric patients.

The Journal of infection·1998
Same author

Membranous lamellar cytoplasmic inclusions in histiocytes and mesothelial cells of serous fluids. Their relationship to phagocytosis of red blood cells.

Acta cytologica·1998
Same author

Transcription from the thyroid hormone-dependent promoter of the Xenopus laevis thyroid hormone receptor betaA gene requires a novel upstream element and the initiator, but not a TATA Box.

The Journal of biological chemistry·1998
Same author

Unique organization and involvement of GAGA factors in transcriptional regulation of the Xenopus stromelysin-3 gene.

Nucleic acids research·1998
Same author

Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70.

Genes & development·1998
Same author

The value of neck drain in esophageal surgery: a randomized trial.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·1998

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Gastroenterology

Background:

  • Hepatocellular carcinoma (HCC) is a significant global health concern.
  • Surgical resection is a primary treatment modality for HCC.
  • Extended hepatectomy for large HCCs requires careful evaluation of outcomes.

Purpose of the Study:

  • To review and analyze the results of extended hepatectomy in patients with hepatocellular carcinoma.
  • To compare the outcomes of extended hepatectomy with lesser liver resections for HCC.
  • To assess the morbidity, mortality, and survival rates associated with extended hepatectomy.

Main Methods:

  • Retrospective review of 25 patients undergoing extended hepatectomy for HCC over 16 years.
  • Comparison with 144 patients who underwent lesser liver resections.

Related Experiment Videos

  • Analysis of tumor size, liver status, postoperative complications, and survival data.

    • Main Results:

    • Extended hepatectomy was performed for tumors ranging from 3 to 20 cm; 68% had non-cirrhotic livers.
    • Major complications included hemorrhage, bile duct injury, and liver failure.
    • 30-day mortality was 12%; median survival was 9.7 months, with 3-year survival at 22%.

    Conclusions:

    • Extended hepatectomy demonstrates comparable morbidity, mortality, and survival to lesser resections for HCC.
    • This procedure is a worthwhile surgical option for large hepatocellular carcinomas.
    • Extended hepatectomy serves as a viable alternative to liver transplantation for select patients.