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Idiopathic cardiomyopathies in Korean children. - 9-Year Korean Multicenter Study-

Jin Hee Oh1, Young Mi Hong, Jae Young Choi

  • 1Department of Pediatrics, The Catholic University of Korea, Seoul, Korean.

Circulation Journal : Official Journal of the Japanese Circulation Society
|July 13, 2011
PubMed

Insights

This study reports the epidemiology of childhood cardiomyopathies (CMPs) in Korea, finding an annual occurrence of 0.28 per 100,000 children. Dilated CMP was the most common type, with varying survival rates among subtypes.

Area of Science:

  • Pediatric Cardiology
  • Epidemiology
  • Cardiovascular Diseases

Background:

  • Idiopathic cardiomyopathies (CMPs) are a heterogeneous group of heart muscle diseases.
  • Epidemiologic data on CMPs are crucial for advancing therapeutic strategies.
  • Limited data exist on CMPs in Asian children, necessitating regional studies.

Purpose of the Study:

  • To conduct a retrospective epidemiologic study of primary cardiomyopathies in Korean children.
  • To determine the incidence and prevalence of different CMP subtypes in this population.
  • To analyze survival rates for various CMP classifications in children.

Main Methods:

  • A multicenter survey was conducted from January 1998 to December 2006.
  • Data were collected from 17 cardiovascular centers in Korea.
  • Patients were classified according to the American Heart Association's 2006 CMP classification.

Main Results:

  • A total of 277 primary CMP patients were identified among Korean children.
  • The average annual occurrence of new CMP cases was 0.28 per 100,000 children (<15 years).
  • Dilated CMP (DCMP) was the most prevalent (66.43%), followed by hypertrophic CMP (HCMP) (23.47%) and restrictive CMP (RCMP) (6.50%).
  • The point prevalence of primary CMP was estimated at 2.11/100,000 children.
  • Nine-year survival rates were 69.8% for DCMP, 90.3% for HCMP, and 47.2% for RCMP.

Conclusions:

  • The recent point prevalence of childhood primary CMP in Korea is estimated at 2.11/100,000.
  • Dilated CMP is the most common subtype in Korean children.
  • Further nationwide epidemiologic studies are recommended to refine these findings.
Abstract

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