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Related Experiment Video

Updated: May 31, 2026

Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse

Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse

Published on: April 17, 2019

Mirena, an Italian experience.

C Bastianelli¹, M Farris, S Rapiti

¹Department of Obstetrics and Gynecology, La Sapienza University, Rome, Italy. carlo.bastianelli@uniroma1.it

Minerva Ginecologica

|July 13, 2011

Summary

This summary is machine-generated.

The levonorgestrel-releasing intrauterine device (Mirena®) demonstrated 100% contraceptive efficacy in Italian women over 7,308 months. This effective contraceptive also reduced menstrual bleeding and was well-tolerated, particularly for heavy menstrual bleeding.

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Area of Science:

Reproductive Medicine
Gynecology
Contraception

Background:

Intrauterine contraception, specifically the levonorgestrel-releasing intrauterine system (Mirena®), is underutilized in Italy.
Understanding its efficacy, patient compliance, and impact on menstrual cycles is crucial for broader adoption.

Purpose of the Study:

To evaluate the contraceptive effectiveness of the levonorgestrel-releasing intrauterine device (Mirena®).
To assess patient compliance and adherence to the Mirena® device.
To analyze the effects of Mirena® on menstrual cycle patterns in an Italian population.

Main Methods:

A prospective study involving 128 women who accepted Mirena® insertion.
Data collection over 48 months, including general and pelvic examinations with ultrasound scans.
Participants maintained menstrual diaries to track bleeding patterns and side effects.

Main Results:

Achieved 100% contraceptive efficacy with zero pregnancies over 7,308 woman-months of observation.
Significant reduction in menstrual blood loss quantity and duration; 29.5% experienced amenorrhea within six months.
High user satisfaction, with only minor side effects like breast tenderness and transient ovarian cysts reported; few removals due to amenorrhea intolerance.

Conclusions:

Mirena® is a safe and highly effective contraceptive method, especially for women with heavy or prolonged menstrual bleeding.
Despite initial underacceptance in Italy, Mirena® offers significant benefits for menstrual cycle regulation and contraception.
The device demonstrates good tolerability, with minimal adverse events impacting long-term use.