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06:07
Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
Human immunodeficiency virus therapeutics and pharmacogenomics
U Shankarkumar1, A Shankarkumar, K Ghosh
1National Institute of Immunohaematology, 13 floor, KEM Hospital, Parel, Mumbai, Maharashtra, India.
Indian Journal of Human Genetics
|July 13, 2011
Summary
Pharmacogenomics and pharmacogenetics enable personalized medicine by informing vaccine design and understanding complex diseases. These fields are crucial for tailoring treatments for conditions like cancer, diabetes, and HIV.
Area of Science:
- Genetics and Genomics
- Immunology
- Pharmacology
Background:
- Pharmacogenomics and pharmacogenetics offer a promising avenue for developing personalized treatment strategies.
- These disciplines are vital for advancing basic immunology and peptide-based vaccine design (vaccinomics).
Purpose of the Study:
- To highlight the significance of pharmacogenomics and pharmacogenetics in personalized medicine.
- To underscore their importance in vaccine development and understanding multifactorial diseases.
Main Methods:
- Review of current literature on pharmacogenomics and pharmacogenetics.
- Analysis of applications in immunology, vaccinomics, and clinical drug monitoring.
- Exploration of roles in molecular pathophysiology of complex diseases.
Main Results:
- Pharmacogenomics and pharmacogenetics are foundational for personalized treatment approaches.
- These fields are critical for peptide-based vaccine design and drug monitoring.
- They provide insights into the molecular pathophysiology of multifactorial diseases.
Conclusions:
- Pharmacogenomics and pharmacogenetics are essential for advancing personalized medicine.
- Their application extends to immunology, vaccinomics, and clinical practice.
- Understanding these fields is key to tackling complex diseases like cancer, tuberculosis, and HIV.
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