Prospective Case Study on Characterization of Colorectal Adenomas Comparing AFI with NBI

Aim. Compare the characterization ability of AFI and NBI for colorectal adenomas. Methods. We prospectively enrolled 58 patients with 89 colorectal adenomas detected by white light colonoscopy. Such lesions were subsequently observed with both AFI and NBI and then treated by endoscopic resection. With respect to the 89 lesions, 3 experienced endoscopists retrospectively evaluated the visualization quality of the AFI and NBI images in a blind manner using a three-tier scale based on excellent, fair, and poor criteria. Results. There were 54, 31, and 4 lesions considered as excellent, fair, and poor visualization, respectively, using AFI in comparison to 53, 19, and 17 lesions, respectively, with NBI. The percentage of excellent and fair visualization lesions was 95.5% with AFI and 80.9% with NBI (P < .01). Conclusion. This study indicated that AFI may be more effective for the characterization of colorectal adenomas because of better visualization of such lesions compared to NBI.