Perioperative mechanical circulatory support in children with critical heart disease

Paul A Checchia1

  • 1Divisions of Critical Care Medicine and Cardiology, St. Louis Children's Hospital, Washington University School of Medicine, One Children's Place, NWT 8th Floor, St. Louis, MO, 63110, USA, pchecchia@wustl.edu.

Insights

Mechanical circulatory support devices offer a vital "bridge" for patients with cardiovascular failure, improving survival in critical situations like cardiac arrest. Optimal timing and patient selection are key to maximizing the benefits of these life-saving interventions.

Area of Science:

  • Cardiology
  • Critical Care Medicine
  • Biomedical Engineering

Background:

  • Mechanical circulatory support (MCS) is a recognized treatment for perioperative cardiovascular failure.
  • MCS devices function as a "bridge" to survival, recovery, or further decision-making.
  • Indications include myocarditis, acute myocardial insult, post-surgical low cardiac output, and congenital heart disease.

Purpose of the Study:

  • To discuss the role and application of mechanical circulatory support in managing cardiovascular failure.
  • To highlight the "bridge" concept in various clinical scenarios, including cardiac arrest.
  • To emphasize the importance of appropriate patient selection and monitoring for effective MCS deployment.

Main Methods:

  • Review of the established use of mechanical circulatory support devices.
  • Discussion of clinical scenarios where MCS is applied, such as cardiac arrest and perioperative decompensation.
  • Emphasis on risk minimization strategies (bleeding, infection, thrombosis) for safe MCS utilization.

Main Results:

  • MCS can salvage patients with otherwise certain mortality, particularly during cardiac arrest.
  • The effectiveness of MCS is most pronounced in patients not at the extremes of the survival curve.
  • Risk management strategies can minimize complications associated with MCS.

Conclusions:

  • The timely and appropriate application of MCS is crucial for optimizing patient outcomes.
  • A "not too early, not too late" approach, guided by careful monitoring, is essential for successful MCS therapy.
  • Multidisciplinary team involvement is vital in selecting patients and managing MCS interventions.
Abstract