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Updated: May 31, 2026

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
Successful treatment of a very rare case: locally treated cervical rhabdomyosarcoma
Erbil Karaman1, Ozgur Akbayir, Yasemin Kocatürk
1Department of Obstetrics and Gynecology, Bakirkoy Women's Health and Children's Research Hospital, Istanbul, Turkey. Erbil84@gmail.com
Aim:
To study the local treatment of uterine cervical rhabdomyosarcoma in which fertility-sparing surgery is done.
Methods:
We report an embryonal rhabdomyosarcoma of the uterine cervix which presented as a cervical polyp in a 22-year-old nulliparous woman.
Results:
The tumor was composed of rhabdomyoblasts of varying differentiation dispersed within a loose, myxoid stroma, and formed a distinct cambium layer beneath the epithelium. The patient was successfully treated with fertility-sparing surgery and adjuvant chemotherapy.
Conclusion:
The treatment modality should be done according to the patients individually. Treatment has recently inclined toward conservative therapy. Patients with favorable prognostic factors such as localized disease, single polyp and embryonal histologic subtype and without deep invasion can be treated with minimal invasive surgery.

