Related Experiment Video
Updated: May 31, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
Diagnostic yield of capsule endoscopy for gastric diseases
Yuka Kobayashi1, Hirotsugu Watabe, Atsuo Yamada
1Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Hongo, Bunkyo-ku, Japan.
Background And Aim:
Capsule endoscopy (CE) for the stomach has not yet been in practical use. Likewise as in colon, CE for colorectal cancer screening, the less invasive nature of CE may be suitable for gastric screening. The aim of this study is to estimate a diagnostic yield of CE for gastric diseases.
Methods:
This study involved 55 patients who participated in other clinical studies regarding obscure overt gastrointestinal bleeding or iron deficiency anemia. All patients underwent esophagogastroduodenoscopy and CE within 2 weeks. Sensitivity and specificity of CE for diffuse and localized gastric lesions were calculated, respectively.
Results:
Gastroscopy revealed 38 diffuse lesions (14 antral gastritis, 19 pangastritis, and 5 diffuse antral vascular ectasia) and 25 localized lesions (14 erosions, 2 cancers, and 9 polyps). CE had a higher sensitivity for gastric diffuse lesions compared with localized lesions. For diffuse lesions, sensitivity and specificity of CE were 70% and 82%, respectively. For localized lesions, sensitivity and specificity of CE were 28% and 63%, respectively. All cancers could not be detected by CE.
Conclusions:
Currently, the diagnostic yield of CE for gastric diseases is not high enough for gastric screening. Additional improvements including preparations, position change, or the invention of new technologies are required.
Related Concept Videos
Endoscopic Procedures III: Video Capsule Endoscopy
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures V: ERCP
Patient...
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
