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[Intracranial meningiomas: I. Epidemiology, aetiology, pathogenesis and prognostic factors]

M Gelabert-González1, R Serramito-García

  • 1Departamento de Cirugía, Facultad de Medicina y Odontología, Universidad de Santiago de Compostela, A Coruña, España. miguel.gelabert@usc.es

Revista De Neurologia
|July 13, 2011
PubMed
Abstract

Insights

Meningiomas are common brain tumors, mostly benign but with recurrence rates of 10-20%. Understanding risk factors and genetics can personalize future treatments for intracranial meningiomas.

Area of Science:

  • Neuro-oncology
  • Neurosurgery

Context:

  • Meningiomas represent the most common primary intracranial tumors, constituting approximately one-third of all brain tumors.
  • These neoplasms originate from the arachnoid mater cells and can occur within the cranial and spinal cavities.

Purpose:

  • To consolidate and update current knowledge on intracranial meningiomas through a comprehensive literature review.
  • To provide an updated overview of epidemiology, histology, risk factors, neurogenetics, diagnostic modalities, and prognostic indicators.

Summary:

  • Intracranial meningiomas are the leading group of intracranial tumors.
  • Despite a predominantly benign histological profile, recurrence rates after complete resection range from 10% to 20%.
  • Identifying risk factors and genetic predispositions is crucial for developing tailored therapeutic strategies.

Impact:

  • Enhanced understanding of meningioma behavior, including recurrence patterns.
  • Facilitates the development of personalized treatment approaches based on individual risk factors and genetic profiles.
  • Contributes to improved patient outcomes and management strategies for intracranial meningiomas.

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