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Updated: May 31, 2026

Partial Lobular Hepatectomy: A Surgical Model for Morphologic Liver Regeneration
Published on: May 31, 2018
[Toxic liver injuries--a current view on pathogenesis. Part I]
Marek Bak1, Maciej Czerniak, Magda Kicińska-Krogulska
1Oddział Toksykologii, Klinika Chorób Zawodowych i Toksykologii, Instytut Medycyny Pracy im. prof. J. Nofera, Łódź.
Abstract:
Toxic liver injury poses an important heath problem in occupational medicine. Toxic response of this organ may arise from acute or chronic exposure to different substances. The final toxicological response to different toxicants may be defined as the regeneration of cells, loss of their function or necrosis. The morphology of toxic drug- or chemical-induced liver injury usuall differentiates into one of the following phenotypes: cholestatic injury, hepato- cellular injury, often associated with elevated l enzymes, mitochondrial injuries and delayed immunological injury. In this article, the authors present current knowledge of the pathogenesis of morphological changes in hepatocytes as the result of exposure to xenobiotics.
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