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Updated: May 31, 2026

Directed Induction of Retinal Organoids from Human Pluripotent Stem Cells
Published on: April 21, 2021
Induced pluripotent stem cell technology for generating photoreceptors
Cédric Boucherie1, Jane C Sowden, Robin R Ali
1Department of Genetics, UCL Institute of Ophthalmology 11-43 Bath Street, London EC1V 9EL, UK.
Abstract:
The discovery of methods to produce pluripotent stem cells from human skin cells and other adult tissues has created a new era in stem cell research. In this article, we discuss the generation and use of pluripotent stem cells for the study of retinal disorders and the development of cell-based therapies. We describe advances in protocols for differentiating pluripotent cells into photoreceptor precursors that might be suitable for transplantation and discuss the use of human induced pluripotent stem cell-derived photoreceptors for disease modeling and drug screening.
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