Related Experiment Video
Updated: May 31, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
Marijuana-induced mania in a healthy adolescent: a case report
Joseph W Iskandar1, Benjamin Griffeth, Taral Sharma
1Carilion Clinic-Virginia Tech Carilion School of Medicine Psychiatry Residency Program, Roanoke, VA 24014, USA. jwiskandar@carilionclinic.org
Abstract:
Marijuana is the most commonly used illegal substance by adolescents in the United States. According to a 2009 survey conducted by Monitoring the Future, there were about 11.8% of 8th graders, 26.7% of 10th graders and 32.8% of 12th graders who had abused marijuana at least once in the year (Johnston L.D., Bachman J.G., O'Malley P.M., Schulenberg J.E. Monitoring the Future: A Continuing Study of American Youth (12th-Grade Survey), 2009 [Computer file]. ICPSR28401-v1. Ann Arbor, MI: Interuniversity Consortium for Political and Social Research [distributor], 2010-10-27. doi:10.3886/ICPSR28401). A retrospective review of published literature disclosed case reports of marijuana-induced mania in adult patients with no prior psychiatric history (Bonnet U., Chang D.I., Wiltfang J., Scherbaum N., Weber R. A case of cannabis-induced mania. Fortschr Neurol Psychiatr. 2010 Apr; 78(4):223-5. Epub 2010 Feb3; Henquet C., Krabbendam L., de Graaf R., ten Have M., van Os J. Cannabis use and expression of mania in the general population. J Affect Disord. 2006 Oct;95(1-3):103-10. Epub 2006 Jun 21). To the best of our knowledge, this is the first report to document that marijuana induced manic symptoms in an adolescent with no known prior psychiatric history.
Related Concept Videos
Mania and Antimanic Drugs: Overview
Bipolar Disorder
Hallucinogens and Psychedelics
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
Drug Therapy
Antianxiety Medications
Altered States of Awareness
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain that...

