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easyDAS: automatic creation of DAS servers.

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GenExp: an interactive web-based genomic DAS client with client-side data rendering.

Bernat Gel Moreno¹, Xavier Messeguer Peypoch

¹Software Department, UPC-BarcelonaTech, Barcelona, Spain. bgel@lsi.upc.edu

|July 14, 2011

Summary

This summary is machine-generated.

GenExp is an interactive, web-based client for the Distributed Annotation System (DAS) that enhances genome exploration. It offers immediate, intuitive navigation and data visualization through client-side rendering.

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Area of Science:

Bioinformatics
Genomics
Data Visualization

Background:

The Distributed Annotation System (DAS) facilitates sharing and integrating biological sequence annotations.
Over 1000 DAS sources exist, with increasing numbers, necessitating effective client-side integration.
Existing web-based DAS clients often lack direct interaction features like zooming and panning.

Purpose of the Study:

To introduce GenExp, a novel, fully interactive, web-based visual client for the Distributed Annotation System (DAS).
To provide an intuitive and efficient platform for exploring genomic data.
To overcome limitations of current DAS clients regarding user interaction and data rendering.

Main Methods:

Developed GenExp as a genome-oriented DAS client utilizing the latest HTML5 web technologies.
Implemented client-side rendering for data representation within the browser.
Enabled intuitive, map-like navigation through genomic data using mouse interactions.

Main Results:

GenExp offers immediate responses to zooming and panning due to client-side rendering, minimizing network requests.
The client allows seamless exploration from base-level detail to entire chromosomes.
GenExp supports multiple simultaneous data viewers and the saving of application states for later review.

Conclusions:

GenExp represents a significant advancement in interactive web-based DAS clients.
Its client-side rendering approach simplifies genome browsing and exploration.
GenExp is open-source (GPL license) and freely accessible for broader use in bioinformatics research.