Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Nursing Assessment01:29

Nursing Assessment

The two sources for collecting information are primary and secondary. After gathering information, interpretation and validation help to complete the data. The purpose of assessment is to establish data with the initial information, to interpret data about the patient's perceived needs and health problems, and to respond to these problems identified.
The nurse collects all aspects of the patient's health in the initial assessment, establishing priorities for ongoing focused assessments and...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Zeitschrift fur Gerontologie und Geriatrie·2026
Same author

[40th anniversary of the German Society of Geriatrics (DGG)-In demand, matured, strengthened : History of the DGG concerning scientific and professional political aspects].

Zeitschrift fur Gerontologie und Geriatrie·2025
Same author

[Geriatric trauma centers - requirements catalog. An initiative to promote and guarantee the quality of care of elderly trauma patients receiving inpatient care].

Zeitschrift fur Gerontologie und Geriatrie·2014
Same author

[Geriatric trauma care in Germany. On the way to providing better care].

Zeitschrift fur Gerontologie und Geriatrie·2014
Same author

[Ten years of early complex geriatric rehabilitation therapy in the DRG system].

Zeitschrift fur Gerontologie und Geriatrie·2014
Same author

[Multimorbidity in elderly rheumatic patients part 1].

Zeitschrift fur Rheumatologie·2013

Related Experiment Video

Updated: May 31, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

[Geriatric assessment. Development, status quo and perspectives].

D Lüttje1, D Varwig, B Teigel

  • 1Medizinische Klinik IV, Geriatrie und Palliativmedizin, Klinikum Osnabrück, Am Finkenhügel 1, 49076 Osnabrück. dieter.luettje@klinikum-os.de.

Der Internist
|July 14, 2011
PubMed
Summary
This summary is machine-generated.

Multimorbidity in geriatric patients requires comprehensive assessment to prevent prolonged hospital stays. Geriatric assessment identifies risks and guides holistic treatment, reducing illness and mortality.

More Related Videos

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Related Experiment Videos

Last Updated: May 31, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Area of Science:

  • Geriatrics
  • Internal Medicine
  • Public Health

Context:

  • Multimorbidity is prevalent in geriatric patients, often overlooked by standard clinical guidelines.
  • Untreated issues can lead to increased hospitalizations and extended stays.
  • Geriatric assessment offers a holistic approach beyond typical clinical evaluations.

Purpose:

  • To highlight the importance of geriatric assessment for identifying and managing complex health issues in older adults.
  • To advocate for the integration of geriatric screening in primary care and emergency settings.
  • To emphasize the role of geriatric assessment in improving patient outcomes and quality of life.

Summary:

  • Geriatric assessment is crucial for identifying hidden problems in older adults with multiple conditions.
  • It facilitates a comprehensive, holistic treatment plan tailored to individual needs.
  • This approach aims to enhance independent living, well-being, and reduce morbidity and mortality.

Impact:

  • Early identification of geriatric patients at risk can prevent adverse health events.
  • Holistic treatment planning improves patient outcomes, including reduced hospitalizations.
  • Integrating specific tools for pain, nutrition, and frailty enhances the standardized geriatric assessment.