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Myocardial bridges: A review
Marios Loukas1, Katrina Von Kriegenbergh, Mathangi Gilkes
1Department of Anatomical Sciences, School of Medicine, St. George's University, Grenada, West Indies. mloukas@sgu.edu
Insights
Myocardial bridges, where heart muscle crosses coronary arteries, can be an anatomical variant. However, they may cause cardiac ischemia through systolic compression or reduced arterial flow, impacting coronary blood flow reserve.
Area of Science:
- Cardiology
- Anatomy
- Pathophysiology
Background:
- Myocardial bridges are common and often asymptomatic, suggesting they can be a normal anatomical variant.
- The clinical significance of myocardial bridges remains debated, with some cases linked to cardiac ischemia.
Purpose of the Study:
- To review the existing evidence on myocardial bridging.
- To explore the potential mechanisms by which myocardial bridges may cause myocardial ischemia.
Main Methods:
- Literature review of studies on myocardial bridging and its clinical implications.
- Analysis of proposed pathophysiological mechanisms for ischemia in myocardial bridging.
Main Results:
- Myocardial bridging can be an anatomical variant, not always causing symptoms.
- Two primary mechanisms are proposed for ischemia: systolic compression and reduced arterial flow.
- Both mechanisms can lead to diminished coronary blood flow reserve.
Conclusions:
- Myocardial bridging has a complex relationship with cardiac ischemia.
- Further research is needed to fully understand the clinical significance and management of myocardial bridges.
Abstract:
Much has been written regarding the potential clinical significance of myocardial bridges. As such bridging is often seen in normal individuals, it is clear that not all arteries bridged by myocardial segments produce clinical symptoms thereby suggesting that this feature may simply be an anatomical variant. However, some authors who have considered these bridges as the cause of cardiac ischemia have suggested two potential mechanisms for their pathophysiology. The first is a phasic systolic compression of the bridged segment with persistent mid-to-late diastolic reduction in arterial diameter and the second proposes a reduction in arterial flow. Both mechanisms may contribute to a reduced reserve in coronary blood flow. In this review, we discuss the evidence that exists regarding myocardial bridging and the potential for bridging to cause myocardial ischemia.
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