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[Application of intravenous immunoglobulin preparations (IVIGs) in organ transplantation]

Grzegorz Senatorski1, Ewa Hryniewiecka

  • 1Klinika Immunologii, Transplantologii i Chorób Wewnetrznych, Instytut Transplantologii Warszawskiego Uniwersytetu Medycznego. gsenat@poczta.onet.pl

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|July 15, 2011
PubMed

In clinical setting intravenous immunoglobulin preparations (IVIGs) are used for over thirty years. They were used initially as a substitutive treatment. Discovering of IVIG immunosuppressive properties has led to its use in the treatment of autoimmune diseases. Since then the range of indications in this group of diseases is becoming wider. With regard to IVIG's multidirectional influence exerted on the immune system it has also find its application in transplantology. In the article IVIG's mechanism of action, possible applications in transplantation and adverse effects are discussed.

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