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Intralymphatic Immunotherapy and Vaccination in Mice
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Intralymphatic Immunotherapy and Vaccination in Mice

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[The rational immunotherapy with intravenous immunoglobulin in neurologic diseases]

Jolanta Korsak1

  • 1Wojskowy Instytut Medyczny w Warszawie, Zakład Transfuzjologii Klinicznej CSK MON.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|July 15, 2011
PubMed

Intravenous immunoglobulins (IVIG) have been used mainly as a supplement therapy in hypogammglobulinemia patients. IVIG have been proved effective in treating TTP and recently they have been used in treating many autoimmune and inflammatory diseases. In neurologic diseases IVIG have immunomodulating features dependent on IgG Fc-fragment. Which diseases benefit from the use of IVIG was the find from controlled clinical trials in accordance with Evidence Based Medicine. IVIG have been proved effective in Guillaine-Barre syndrom, chronic inflammatory demyelinating polyradiculoneuropathy, miastenia, dermathomyositis and sclerosis multiple. The recommendations include the frequency of IVIG administering its dosage and duration of treatment.

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