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Updated: May 31, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
5''-(4-Chloro-benzyl-idene)-4'-(4-chloro-phen-yl)-5-fluoro-1',1''-dimethyl-indoline-3-spiro-2'-pyrrolidine-3'-spiro-3
Abstract:
The piperidine ring of the title compound, C(30)H(26)Cl(2)FN(3)O(2), adopts a twisted chair conformation. The pyrrolidine ring has a twisted envelope structure with the N atom at the flap [displaced by 0.592 (3) Å]. The fluoro-oxindole, chloro-phenyl and chloro-benzyl-idene groups are planar with r.m.s. deviations of 0.0348, 0.0048 and 0.0048 Å, respectively. The structure is stabilized by inter-molecular N-H⋯O hydrogen bonds.
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