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Updated: May 31, 2026
09:54
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
Published on: August 20, 2018
2-[(Dodecylsulfanyl)carbonothioyl-sulfanyl]-propanoic acid
Shude Xiao1, Paul A Charpentier
1Dept. of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario, London, Ontario, Canada N6A 5B9.
Summary
The crystal structure of a decyl compound reveals an extended zigzag decyl chain. Two molecules form a hydrogen-bonded dimer through their hydroxyl groups.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding molecular conformation and intermolecular interactions is crucial in organic chemistry.
- Crystal structure analysis provides detailed insights into molecular arrangements and bonding.
Purpose of the Study:
- To determine the crystal structure of the title compound, C(16)H(30)O(2)S(3).
- To investigate the conformational preferences of the decyl chain.
- To identify and characterize intermolecular interactions, such as hydrogen bonding.
Main Methods:
- Single-crystal X-ray diffraction was employed to analyze the crystal structure.
- The molecular formula C(16)H(30)O(2)S(3) was confirmed.
- The arrangement of molecules in the crystal lattice was elucidated.
Main Results:
- The decyl chain within the molecule adopts an extended, zigzag conformation.
- Two molecules were observed to associate via a center of inversion.
- An O-H⋯O hydrogen bond was identified, forming a dimeric structure.
Conclusions:
- The study elucidates the solid-state structure of the C(16)H(30)O(2)S(3) compound.
- The formation of a hydrogen-bonded dimer is a key feature of its crystal packing.
- The findings contribute to the understanding of molecular self-assembly in organic crystals.
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