Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction01:16

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry01:28

Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

The Diels–Alder reaction is one of the robust methods for synthesizing unsaturated six-membered rings. The reaction involves a concerted cyclic movement of six π electrons: four π electrons from the diene and two π electrons from the dienophile.
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry01:29

Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry

Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
Structure of Conjugated Dienes01:16

Structure of Conjugated Dienes

Introduction
Conjugated dienes are compounds characterized by the presence of alternating double and single bonds. In a conjugated system like 1,3-butadiene, the unhybridized 2p orbital on each carbon overlaps continuously, allowing the π electrons to be delocalized across the entire molecule. In contrast, this type of overlap does not occur in cumulated and isolated dienes, such as 2,3-pentadiene and 1,4-pentadiene, respectively. Instead, the π electrons remain localized between the double...
Diels–Alder Reaction: Characteristics of Dienes01:29

Diels–Alder Reaction: Characteristics of Dienes

The Diels–Alder reaction brings together a diene and a dienophile to form a six-membered ring. Both components have unique characteristics that influence the rate of the reaction.
Characteristics of the diene
Conformation
The simplest example of a diene is 1,3-butadiene, an acyclic conjugated π system. At room temperature, the molecule exists as a mixture of s-cis and s-trans conformers by virtue of rotation around the carbon–carbon single bond. Although the s-trans isomer is more stable, the...
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism01:18

Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism

Birch reduction uses solvated electrons as reducing agents. The reaction converts benzene to 1,4-cyclohexadiene. The reaction proceeds by the transfer of a single electron to the ring to form a benzene radical anion. This anion is highly basic—it abstracts a proton from the alcohol to form a cyclohexadienyl radical. Another single electron transfer gives the cyclohexadienyl anion. A proton transfer from the alcohol forms 1,4-cyclohexadiene. Since this reduction occurs via radical anion...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing the Photophysical Properties of Bridged and Unbridged Platinum(II) Cyclometalated Complexes.

Inorganic chemistry·2026
Same author

Total Synthesis of Orbiculamide A.

Organic letters·2026
Same author

Challenging the Macrocycle Paradigm: Four-Arm, High-Denticity Acyclic Chelators for Radiopharmaceuticals Incorporating Actinium and Lanthanides.

Inorganic chemistry·2026
Same author

Synthon Substitution via C-I···π and C-I···N Halogen Bonds in Cocrystals of Anthracene-Based Organic Semiconductor Isosteres.

Crystal growth & design·2026
Same author

Synthesis and Ring-Opening Polymerization of Antimony(III)-Bridged [1]Ferrocenophanes.

Inorganic chemistry·2026
Same author

Tuning the Excited State Character of Amine/Carbonyl Thermally Activated Delayed Fluorescence Emitters with Ring Fusion.

Chemistry (Weinheim an der Bergstrasse, Germany)·2025

Related Experiment Video

Updated: May 31, 2026

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
07:07

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology

Published on: March 12, 2015

Dibenzyl ferrocene-1,1'-dicarboxyl-ate.

Brian O Patrick, Chris Rock, Alaa S Abd-El-Aziz

    Acta Crystallographica. Section E, Structure Reports Online
    |July 15, 2011
    PubMed
    Summary

    This study reveals distinct molecular orientations in [Fe(C(13)H(11)O(2))(2)] due to phenyl-methoxy-carbonyl group arrangements. Intermolecular interactions form a one-dimensional hydrogen-bonded network, influencing crystal structure.

    Area of Science:

    • Coordination Chemistry
    • Crystal Engineering

    Background:

    • Understanding the structural nuances of metal-organic compounds is crucial for designing materials with specific properties.
    • The role of substituent orientation and intermolecular forces in dictating crystal packing requires further investigation.

    Purpose of the Study:

    • To elucidate the structural characteristics of the iron(II) complex [Fe(C(13)H(11)O(2))(2)].
    • To investigate the influence of phenyl-methoxy-carbonyl substituent orientations on molecular packing.
    • To identify the intermolecular interactions responsible for the observed crystal network.

    Main Methods:

    • Single-crystal X-ray diffraction analysis was employed to determine the molecular and crystal structure.
    • Analysis of C-H⋯O interactions and torsion angles provided insights into substituent orientations.

    More Related Videos

    Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyl(tropone)iron
    07:56

    Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyl(tropone)iron

    Published on: August 12, 2019

    Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
    11:27

    Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

    Published on: December 4, 2016

    Related Experiment Videos

    Last Updated: May 31, 2026

    Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
    07:07

    Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology

    Published on: March 12, 2015

    Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyl(tropone)iron
    07:56

    Preparation of 6-aminocyclohepta-2,4-dien-1-one Derivatives via Tricarbonyl(tropone)iron

    Published on: August 12, 2019

    Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
    11:27

    Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

    Published on: December 4, 2016

  • Topological analysis of the crystal structure identified the hydrogen-bonded network.

    • Main Results:

    • The crystal structure of [Fe(C(13)H(11)O(2))(2)] exhibits two phenyl-methoxy-carbonyl substituents with significantly different orientations (torsion angles of 84.5° and 139.6°).
    • Multiple intermolecular C-H⋯O interactions were identified as the mediating forces for these distinct orientations.
    • These interactions facilitate the formation of a one-dimensional hydrogen-bonded network within the crystal.

    Conclusions:

    • The varied orientations of the substituents are a key feature of this iron(II) complex.
    • Intermolecular C-H⋯O interactions play a vital role in directing crystal packing and network formation.
    • The resulting one-dimensional hydrogen-bonded network influences the overall supramolecular architecture.