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Updated: May 31, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
1,5-Bis(1-phenyl-ethyl-idene)thio-carbono-hydrazide
This study reveals the non-planar structure of a C(17)H(18)N(4)S molecule. Intermolecular hydrogen bonds form inversion dimers in its crystal structure.
Area of Science:
- Crystallography
- Molecular Structure
- Supramolecular Chemistry
Background:
- Understanding molecular geometry is crucial for predicting chemical properties.
- Crystal packing influences material characteristics.
- Hydrogen bonding plays a key role in molecular assembly.
Purpose of the Study:
- To determine the three-dimensional structure of the title molecule.
- To investigate intermolecular interactions in the solid state.
- To characterize the crystal structure of C(17)H(18)N(4)S.
Main Methods:
- Single-crystal X-ray diffraction was employed.
- Analysis of dihedral angles between aromatic rings.
- Identification of hydrogen bonding networks.
Main Results:
- The molecule exhibits a non-planar conformation with a dihedral angle of 27.24(9)° between benzene rings.
- In the crystal lattice, N-H⋯S hydrogen bonds were observed.
- These interactions lead to the formation of centrosymmetric inversion dimers.
Conclusions:
- The studied molecule possesses a twisted geometry.
- Intermolecular hydrogen bonding dictates the supramolecular architecture.
- The formation of dimers is a significant feature of the crystal packing.
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