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Updated: May 31, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
(E)-3-[4-(Dimethyl-amino)-phen-yl]-1-(2-methyl-4-phenyl-quinolin-3-yl)prop-2-en-1-one 0.7-hydrate
Abstract:
In the title compound, C(27)H(24)N(2)O·0.7H(2)O, the quinoline ring system is approximately planar, with a maximum deviation of 0.011 (1) Å, and forms dihedral angles of 74.70 (4) and 80.14 (4)° with the phenyl and benzene rings, respectively. In the crystal, the mol-ecules are linked to the water mol-ecules via inter-molecular O-H⋯N hydrogen bonds and further stabilized by C-H⋯π inter-actions involving the centroid of the benzene ring of the quinoline group. This benzene ring is observed to form a π-π inter-action with an adjacent pyridine ring [centroid-centroid distance = 3.7120 (6) Å].
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