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Updated: May 31, 2026

10:44
Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
Published on: May 15, 2019
3a,8a-Dihy-droxy-1,3,3a,8a-tetra-hydro-indeno-[1,2-d]imidazole-2,8-dione
Abstract:
In the title mol-ecule, C(10)H(8)N(2)O(4), the imidazolidine ring adopts a twisted conformation. In the crystal, the mol-ecules are linked via a pair of bifurcated inter-molecular O-H⋯O hydrogen bonds, forming an inversion dimer. The dimers are further linked via N-H⋯O hydrogen bonds into a tape along the b axis.

