Resistant hypertension and obstructive sleep apnea in the primary-care setting
1Brooklyn Center for Health Disparities, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, P.O. Box 1199, Brooklyn, NY 11203-2098, USA.
International Journal of Hypertension
|July 15, 2011
Summary
Resistant hypertension (RH) affects 26% of Black patients in primary care. Those with RH face a significantly higher risk of obstructive sleep apnea (OSA) compared to general hypertensive patients.
Area of Science:
- Cardiology
- Sleep Medicine
- Public Health
Background:
- Resistant hypertension (RH) is a significant clinical challenge, particularly in hypertensive populations.
- Obstructive sleep apnea (OSA) is a common comorbidity associated with cardiovascular disease.
Purpose of the Study:
- To determine the prevalence of resistant hypertension (RH) among Black patients.
- To investigate the association between RH and the risk of obstructive sleep apnea (OSA).
Main Methods:
- Utilized data from the Metabolic Syndrome Outcome Study (MetSO) involving 200 hypertensive Black patients.
- Defined RH using JNC 7 and European Society guidelines.
- Assessed OSA risk using the Apnea Risk Evaluation System (ARES), with high risk defined as a score ≥6.
Main Results:
- The prevalence of RH was 26% among the study participants.
- 40% of patients were identified as being at high risk for OSA.
- After adjusting for covariates, RH patients were 2.46 times more likely to be at high OSA risk (OR = 2.46, 95% CI: 1.03-5.88, P < .05).
Conclusions:
- The prevalence of RH in this Black population aligns with general hypertensive populations.
- Patients with RH demonstrate a significantly elevated risk for OSA compared to those with non-resistant hypertension.
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