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Updated: May 31, 2026

Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of Gold(III)
Published on: August 31, 2018
Gold compounds as therapeutic agents for human diseases
Susan J Berners-Price1, Aleksandra Filipovska
1Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland 4222, Australia. s.berners-price@griffith.edu.au
Gold compounds show renewed promise as versatile drugs for various diseases. Research focuses on targeting cellular components to treat cancers, arthritis, and infections by addressing protein dysfunction.
Area of Science:
- Medicinal Chemistry
- Nanomedicine
- Pharmacology
Background:
- Gold compounds have a long history in medicine, notably Au(I) for rheumatoid arthritis.
- Recent research explores novel gold(I) and gold(III) compounds for diverse therapeutic applications.
- Understanding gold's mechanism of action is key to developing new disease treatments.
Purpose of the Study:
- To discuss the rationale behind designing gold compounds for specific cellular targets.
- To highlight recent advancements and discoveries in gold-based drug development.
- To explore the potential of gold compounds in treating diseases linked to protein dysfunction.
Main Methods:
- Review of existing literature on gold compounds in medicine.
- Analysis of recent research findings on gold-based drug design and application.
- Discussion of novel discoveries and their implications for disease treatment.
Main Results:
- Gold compounds are being developed to target cellular components in cancer, arthritis, and infectious diseases.
- New disease targets have been identified, enhancing understanding of gold compound mechanisms.
- Gold compounds show potential for treating diseases related to selenol and thiol protein dysfunction.
Conclusions:
- Gold compounds offer a versatile platform for developing powerful new drugs.
- Targeted design of gold compounds can alleviate symptoms of various human diseases.
- Further research into gold's interaction with selenol and thiol proteins is warranted.
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