Related Experiment Video
Updated: May 31, 2026
Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
Published on: September 2, 2025
Total knee arthroplasty for advanced osteoarthritis in the anterior cruciate ligament deficient knee
Guillaume Demey1, Robert A Magnussen, Sébastien Lustig
1Centre Albert Trillat, Hôpital de la Croix-Rousse, 103, Grande Rue de la Croix Rousse, 69004, Lyon, France. guillaume.demey@chu-lyon.fr
Purpose:
Little is known about intra-operative difficulties and outcomes of TKA in ACL deficient knees.
Methods:
Fifty-seven osteoarthritic knees (mean age 70 years) with a history of ACL injury underwent posterior-stabilised TKA. Intra-operative findings and results were compared with a matched control group.
Results:
Difficult tibial exposure and bone loss were noted in the ACL-deficient group leading to one partial patellar tendon avulsion and one femoral condylar fracture. After three years, no infections or revisions occurred. No differences were noted in ROM, IKS knee score (95 ± 6 versus 93 ± 8, p = 0.1), IKS function score (83± 19 versus 84 ± 16, p = 0.7), or radiolucent line presence.
Conclusions:
Total knee arthroplasty in ACL deficient knees is effective. Difficulty obtaining tibial exposure and posteromedial tibial bone defects should be anticipated. Outcomes are comparable to standard primary TKA.
