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Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Mitochondria01:37

Mitochondria

Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...

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[Esthetic dermatology-new developments and safety aspects].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2021
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[Skin quality and ways to improve skin quality].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2021
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[Topical treatment of pigmentation disorders with cosmetic and pharmaceutical agents].

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Polyphenols as active ingredients for cosmetic products.

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Mechanical properties of human skin in vivo: a comparative evaluation in 300 men and women.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2013
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Related Experiment Video

Updated: May 31, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
03:47

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

[Anti-aging creams. What really helps?].

M Kerscher1, H Buntrock

  • 1Department Chemie, Studiengang Kosmetikwissenschaft, Universität Hamburg. martina.kerscher@uni-hamburg.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|July 15, 2011
PubMed
Summary

Discover evidence-based cosmeceutical ingredients for skin aging, focusing on antioxidants like vitamin C and cell regulators such as retinol. Quality is determined by scientifically proven efficacy and safety.

Area of Science:

  • Dermatology and Cosmeceutical Science

Background:

  • Growing importance of youth and beauty drives cosmeceutical innovation.
  • Recent years have seen a surge in the development of new cosmeceutical products.

Purpose of the Study:

  • To describe new, evidence-based ingredients for combating skin aging.
  • To highlight key antioxidants and cell regulators used in modern cosmeceuticals.

Main Methods:

  • Review of scientific literature on cosmeceutical ingredients.
  • Focus on antioxidants (e.g., vitamin C, niacinamide, polyphenols, flavonoids).
  • Focus on cell regulators (e.g., retinol, peptides, growth factors).

Main Results:

  • Identified key antioxidants and cell regulators with anti-aging properties.

Related Experiment Videos

Last Updated: May 31, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
03:47

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

  • Emphasized the importance of in-vivo and in-vitro efficacy data.
  • Highlighted the need for scientifically approved wanted and unwanted effects.
  • Conclusions:

    • Evidence-based efficacy and safety are crucial for cosmeceutical quality.
    • Antioxidants and cell regulators represent key ingredient classes for skin aging.
    • Scientific validation underpins the development of effective cosmeceuticals.