Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Chickenpox01:20

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cross-Talk between Neurons and Immune Cells in Pruritus: from Mechanisms To Medicines.

Current allergy and asthma reports·2026
Same author

Sleep Disturbance as a Mediator Between Itch and Quality of Life.

JAMA dermatology·2026
Same author

Epigenetic Modification in Preclinical and Clinical Dermatological Itch Conditions.

European journal of pain (London, England)·2026
Same author

Ethical considerations for managing psychogenic pruritus in patients with delusional parasitosis.

Journal of the American Academy of Dermatology·2026
Same author

Lebrikizumab Improves Clinical Manifestations, Symptoms, and Quality of Life in Patients with Moderate-to-Severe Atopic Dermatitis Previously Treated with Dupilumab: Results from the ADapt Study.

Dermatology and therapy·2026
Same author

Feasibility and Patient Experiences in a WhatsApp-Based Educational Pilot for Spanish-Speaking Adults With Chronic Spontaneous Urticaria.

International journal of dermatology·2026
Same journal

Active surveillance for basal cell carcinoma: experiences of patients and proxies.

The Journal of dermatological treatment·2026
Same journal

Severe cutaneous adverse reactions associated with systemic antibiotics in acne vulgaris: a systematic review.

The Journal of dermatological treatment·2026
Same journal

Intralesional human papillomavirus vaccination for cutaneous verrucae: a systematic review and meta-analysis of therapeutic efficacy.

The Journal of dermatological treatment·2026
Same journal

JAK inhibitor-associated acne: a mechanistic paradox with important clinical implications.

The Journal of dermatological treatment·2026
Same journal

Efficacy of vunakizumab in patients with moderate-to-severe plaque psoriasis across diverse disease features: a <i>post hoc</i> analysis of a phase-III trial.

The Journal of dermatological treatment·2026
Same journal

Predictors of optimal disease control in atopic dermatitis with abrocitinib: a real-world study.

The Journal of dermatological treatment·2026
See all related articles

Related Experiment Video

Updated: May 31, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Erythrodermic verrucous psoriasis.

Ashley R Curtis1, Gil Yosipovitch

  • 1Department of Dermatology, Wake Forest University School of Medicine, 4618 Country Club Road, Winston-Salem, NC 27104, USA. acurtis@wfubmc.edu

The Journal of Dermatological Treatment
|July 16, 2011
PubMed
Summary
This summary is machine-generated.

Erythrodermic verrucous psoriasis, a rare condition, presents as extensive, thick plaques. This case highlights a unique, widespread variant of verrucous psoriasis previously unreported in medical literature.

More Related Videos

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Related Experiment Videos

Last Updated: May 31, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Verrucous psoriasis is a rare clinical variant of psoriasis.
  • It is characterized by verrucous plaques and shares histological features with warts but is negative for human papillomavirus (HPV).

Observation:

  • A 46-year-old male presented with an 8-year history of extensive, malodorous, symmetric, verrucous plaques causing erythroderma.
  • Histopathology revealed epidermal hyperplasia, papillomatosis, parakeratosis with neutrophils, and dilated dermal papillae vessels.
  • Tests for HPV DNA and T-cell gene rearrangement were negative.

Findings:

  • The patient was diagnosed with erythrodermic verrucous psoriasis, a presentation not previously documented.
  • This diagnosis was supported by clinical presentation and biopsy findings, excluding HPV infection.

Implications:

  • This case expands the known spectrum of verrucous psoriasis presentation.
  • Recognizing erythrodermic verrucous psoriasis is crucial for accurate diagnosis and management of this rare dermatological condition.