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Radiolabeling of cramoll 1,4: evaluation of the biodistribution
Beatriz Ferreira de Carvalho Patricio1, Maria Helena Madruga Lima-Ribeiro, Maria Tereza Dos Santos Correia
1Laboratory of Nanoradiopharmaceuticals, Academical Hospital Clementino Fraga Filho, 21941-913 Rio de Janeiro, RJ, Brazil.
International Journal of Peptides
|July 16, 2011
Abstract:
The cramoll 1,4 is a well-studied lectin. However, few studies about its biodistribution have been done before. In this study, we radiolabeled the cramol 1,4 with Tc-99m and analyzed the biodistribution. The results showed that the cramol has an abnormal uptake by the bowel with reflections on its clearance mechanism.

