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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
A spontaneous decrease of blood pressure occurs in acute ischemic stroke with favourable neurological course
P Rossi1, C Mandelli, D Manganaro
1Department of Emergency Medicine, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Itlay.
The Open Neurology Journal
|July 16, 2011
Summary
Blood pressure (BP) in acute ischemic stroke does not predict stroke severity or early outcomes. Patients experiencing neurological improvement show a reduction in BP profiles, suggesting a dynamic relationship.
Area of Science:
- Neurology
- Cardiology
- Clinical Research
Background:
- The relationship between blood pressure (BP) and clinical outcomes in acute ischemic stroke is not well-defined.
- Understanding this association is crucial for managing stroke patients effectively.
Purpose of the Study:
- To investigate the association between BP measurements and stroke severity in the acute phase.
- To determine if early changes in neurological status influence BP profiles.
- To explore the predictive value of admission BP for early neurological improvement.
Main Methods:
- 57 patients with acute ischemic stroke were enrolled.
- Blood pressure (BP) was measured using a standard sphygmomanometer on admission and 24-hour ambulatory BP monitoring (ABPM) on days 1 and 6.
- Patients were categorized by neurological deficit severity (NIHSS score) and early neurological improvement (≥4-point NIHSS reduction by day 6).
Main Results:
- Admission sphygmomanometric systolic BP was higher in mild/moderate stroke (NIHSS ≤ 10) compared to moderate/severe (NIHSS > 10), but ABPM showed no difference.
- No significant differences in admission BP or ABPM were found between groups with and without early neurological improvement.
- Clinically improved patients (group C) exhibited a significant reduction in systolic BP from day 1 to day 6 (p < 0.05) compared to non-improved patients (group D).
Conclusions:
- Admission blood pressure does not correlate with stroke severity or predict early neurological outcomes.
- Patients demonstrating early neurological improvement experience a concurrent reduction in their BP profile.
- These findings highlight a dynamic interplay between neurological recovery and BP regulation post-stroke.
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