Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Acute Respiratory Failure-II

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:

Atelectasis II: Pathophysiology

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...

Pneumothorax-I

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Pneumothorax II: Pathophysiology

Pneumothorax II: Pathophysiology

Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...

Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Carbon sequestration potential of high-altitude afforestation in the Eastern Central Alps.

Journal of environmental management·2026

Same author

Comparative analysis of cryoballoon versus radiofrequency catheter ablation in atrial fibrillation patients with impaired left ventricular ejection fraction.

International journal of cardiology. Heart & vasculature·2025

Same author

Impact of encorafenib on survival of patients with BRAF<sup>V600E</sup>-mutant metastatic colorectal cancer in a real-world setting.

Journal of cancer research and clinical oncology·2023

Same author

[Legal aspects of telemedicine in cardiology in Germany].

Herzschrittmachertherapie & Elektrophysiologie·2023

Same author

Smaller panel, similar results: genomic profiling and molecularly informed therapy in pancreatic cancer.

ESMO open·2023

Same author

Open retropubic radical prostatectomy: Still a well-established surgical technique for prostate cancer management.

Actas urologicas espanolas·2022

Search research articles

Related Experiment Video

Updated: May 31, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

[Hypoxemia 4 month after right-sided pneumonectomy].

O Mühling¹, M Koller, A Langbein

¹Fachbereich Kardiologie, Herz- und Gefäßklinik, Rhön Klinik AG, Salzburgerleite 1, 97616 Bad Neustadt Saale. olaf.muehling@kardiologie-bad-neustadt.de

|July 16, 2011

Summary

Platypnea-orthodeoxia syndrome, a rare condition, can cause shortness of breath after lung surgery. Interventional closure of a right-to-left shunt through a persistent foramen ovale successfully improved oxygen levels and reduced dyspnea in a post-pneumonectomy patient.

More Related Videos

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

Related Experiment Videos

Last Updated: May 31, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

Area of Science:

Cardiology
Pulmonology
Medical Interventions

Background:

A 64-year-old male experienced progressive dyspnea four months post-right pneumonectomy for lung cancer.
Symptoms suggested platypnea-orthodeoxia syndrome, characterized by decreased oxygen saturation in an upright position.

Observation:

A 64-year-old male presented with worsening dyspnea four months after right pneumonectomy for lung cancer.
Symptoms included decreased oxygen saturation in the upright position, indicative of platypnea-orthodeoxia syndrome.
Imaging revealed right hemidiaphragm and liver shift compressing the right atrium.

Findings:

A right-to-left shunt through a persistent foramen ovale was confirmed via right heart catheterization.
This shunt was caused by the elevated diaphragm and liver impinging on the right atrium.
Interventional closure of the shunt led to immediate improvement.

Implications:

Interventional closure is an effective treatment for post-pneumonectomy platypnea-orthodeoxia syndrome.
This approach can rapidly restore arterial oxygenation and alleviate dyspnea.
Highlights the importance of considering rare cardiopulmonary complications after thoracic surgery.