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Updated: May 31, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
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[Influence of different processing methods on Angelica sinensis polysaccharides from same origin].

Jieli Lv1, Hongli Chen, Jinao Duan

  • 1College of Pharmacy, Xinxiang Medical University, Xinxiang 453003, China. ruoxin0371@163.com

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|July 19, 2011
PubMed
Summary

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Processing Angelica sinensis affects polysaccharide content and immune function. Microwave drying yielded the highest Angelica sinensis polysaccharides (APS) with significant lymphocyte proliferation, unlike far-infrared drying.

Area of Science:

  • Phytochemistry
  • Immunology
  • Food Science

Context:

  • Angelica sinensis is a traditional herb with potential health benefits.
  • Polysaccharides are key bioactive compounds in medicinal plants.
  • Optimizing extraction and processing methods is crucial for maximizing therapeutic potential.

Purpose:

  • To investigate how different processing techniques influence the yield and biological activity of Angelica sinensis polysaccharides (APS).
  • To compare the effects of various drying methods on APS content and lymphocyte proliferation.
  • To identify optimal processing conditions for enhancing the immunomodulatory properties of APS.

Summary:

  • Phenol-sulfuric acid and carbazole-sulfuric acid methods quantified neutral and acidic polysaccharides, respectively.

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  • Lymphocyte proliferation was assessed using the MTT assay with varying APS concentrations.
  • Microwave drying at medium heat resulted in the highest APS content (26.03%) and demonstrated significant immune-enhancing effects on spleen lymphocytes and T cells.

    • Impact:

    • Processing methods significantly alter APS content and immunomodulatory activity.
    • Microwave drying medium-fired is a promising method for maximizing APS yield and immune enhancement.
    • Findings provide valuable insights for the effective processing of Angelica sinensis for pharmaceutical and nutraceutical applications.