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Related Concept Videos

Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Polymers02:34

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...
Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
Molecular Weight of Step-Growth Polymers01:08

Molecular Weight of Step-Growth Polymers

Step growth polymerization involves bi or multifunctional monomers. Bifunctional monomers react to form linear step growth polymers, whereas multifunctional monomers react to form non-linear or branched polymers.
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...

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Updated: May 31, 2026

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
10:58

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries

Published on: September 6, 2012

Supramolecular polymerization from polypeptide-grafted comb polymers.

Jing Wang1, Hua Lu, Ranjan Kamat

  • 1Polymer Program, Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, USA.

Journal of the American Chemical Society
|July 19, 2011
PubMed
Summary
This summary is machine-generated.

Scientists created new polypeptide-grafted comb polymers for controlled supramolecular polymerization. These synthetic polymers form stable, protein-like tubular structures, advancing macromolecular self-assembly.

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Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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Last Updated: May 31, 2026

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
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OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy
08:34

OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy

Published on: February 5, 2020

Area of Science:

  • Supramolecular Chemistry
  • Polymer Science
  • Materials Science

Background:

  • Protein-inspired helical and tubular structures drive research into synthetic supramolecular polymers.
  • Achieving controlled supramolecular polymerization with large synthetic macromolecules is challenging due to difficulties in monomer structure and interaction control.

Purpose of the Study:

  • To synthesize polypeptide-grafted comb polymers.
  • To utilize tunable secondary interactions in solution for controlled supramolecular polymerization.
  • To create stable, protein-like tubular supramolecular structures.

Main Methods:

  • Synthesis of polypeptide-grafted comb polymers.
  • Exploration of tunable secondary interactions in solution for polymerization.
  • Characterization of the resulting supramolecular structures (tubes).
  • Demonstration of general applicability using gold nanoparticles.

Main Results:

  • Successful synthesis of polypeptide-grafted comb polymers.
  • Controlled supramolecular polymerization achieved through tunable secondary interactions.
  • Formation of stable tubular supramolecular structures with dimensions in the hundreds of nanometers (diameter) and tens of micrometers (length).
  • Demonstrated applicability using polypeptide-grafted gold nanoparticles.

Conclusions:

  • Highly specific intermolecular interactions between macromolecular monomers enable cooperative supramolecular polymer growth.
  • The developed strategy allows for the creation of synthetic supramolecular polymers that mimic biological superstructures.
  • This approach offers a versatile platform for designing complex macromolecular assemblies.