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Evaluation of a novel index by tissue Doppler imaging in patients with advanced heart failure: relation to functional

C-H Lee1, F-C Lin, C-C Chen

  • 1Second Section of Cardiology, Department of Internal Medicine, Heart Failure Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan.

International Journal of Clinical Practice
|July 19, 2011
PubMed

Insights

The EAS index effectively differentiates heart failure severity and predicts cardiac events, offering added value beyond standard echocardiography for advanced heart failure patients.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Tissue Doppler imaging (TDI) assesses left ventricular (LV) function in heart failure.
  • The added value of TDI to predict outcomes in advanced heart failure remains unclear.

Purpose of the Study:

  • To evaluate the predictive value of TDI, including a combined EAS index, for heart failure severity and outcomes.
  • To determine if TDI provides additional information beyond clinical and conventional echocardiographic measures.

Main Methods:

  • Assessed pulsed-wave TDI (PWTDI) parameters, including peak systolic (Sm), early (Em), and late diastolic (Am) velocities.
  • Calculated a combined EAS index of systolic and diastolic performance.
  • Followed 230 heart failure patients for cardiac mortality and hospitalizations.

Main Results:

  • Patients with NYHA functional class III-IV had a significantly higher EAS index compared to class I-II and controls.
  • The EAS index and chronic renal insufficiency (CRF) were independent predictors of functional class.
  • EAS index, LV mass index, and CRF predicted cardiac mortality and hospitalizations.

Conclusions:

  • The EAS index effectively differentiates between functional classes I-II and III-IV heart failure patients.
  • The EAS index correlates with cardiac mortality and hospitalizations, providing value beyond conventional echocardiography.
Abstract

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