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Bridging structure and process in developmental biology through new imaging technologies.

Jennifer Lippincott-Schwartz1

  • 1Eunice Kennedy Shriver Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. lippincj@mail.nih.gov

Developmental Cell
|July 19, 2011
PubMed
Summary

Advancements in imaging technologies are crucial for developmental biology discoveries. Emerging imaging capabilities offer new ways to visualize and study developmental processes across scales.

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Area of Science:

  • Developmental Biology
  • Microscopy
  • Biotechnology

Background:

  • Developmental biology relies heavily on visualizing dynamic biological processes.
  • Technological innovation in imaging is essential for understanding complex life cycles.
  • Past discoveries have been enabled by improvements in imaging resolution and speed.

Purpose of the Study:

  • To survey recent advancements in imaging technologies relevant to developmental biology.
  • To highlight emerging imaging capabilities with significant potential impact.
  • To provide an outlook on future directions in biological imaging.

Main Methods:

  • Literature review of recent imaging technology developments.
  • Analysis of imaging techniques applicable to multiple spatial and temporal scales.
  • Focus on technologies poised for major contributions to developmental biology.

Main Results:

  • Identification of key trends in microscopy and imaging.
  • Highlighting of novel techniques for live-cell and whole-organism imaging.
  • Discussion of improved capabilities in high-resolution, high-speed imaging.

Conclusions:

  • Imaging technology is a critical driver of progress in developmental biology.
  • Emerging technologies promise to revolutionize the study of development.
  • Continued innovation in imaging will unlock new biological insights.