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Pyridoxamine protects protein backbone from oxidative fragmentation.

Sergei Chetyrkin1, Missy Mathis, W Hayes McDonald

  • 1Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Biochemical and Biophysical Research Communications
|July 19, 2011
PubMed
Summary

Pyridoxamine (PM) protects proteins from oxidative damage, including backbone fragmentation. This hydroxyl radical scavenging mechanism may enhance its therapeutic effects for chronic diseases like diabetic nephropathy.

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