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Related Concept Videos

Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
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Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...

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Updated: May 31, 2026

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
05:42

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Published on: October 25, 2024

Gynecological fertility-sparing surgery.

D Vitobello1, G Siesto, C Bulletti

  • 1Department of Gynecology, Cancer Center, IRCCS Humanitas Clinical Institute, Via Manzoni 56, 20089 Rozzano, Milan, Italy. domenico.vitobello@tin.it

Placenta
|July 19, 2011
PubMed
Summary
This summary is machine-generated.

Fertility-sparing surgeries offer young women with early-stage gynecologic cancers a chance to preserve childbearing potential. This review examines oncologic and fertility outcomes of these vital procedures.

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Area of Science:

  • Gynecologic Oncology
  • Reproductive Medicine
  • Oncology

Background:

  • Improved survival in gynecologic cancers highlights the need to address quality of life.
  • Traditional treatments often sacrifice fertility, impacting young women's reproductive choices.
  • Fertility preservation is a growing concern for young women diagnosed with gynecologic malignancies.

Purpose of the Study:

  • To review the current literature on fertility-sparing procedures for gynecologic cancers.
  • To evaluate the oncologic safety and fertility outcomes of these organ-preserving techniques.
  • To assess the feasibility of fertility-sparing options for young women with early-stage disease.

Main Methods:

  • Comprehensive literature search of studies on fertility-sparing surgeries for cervical, endometrial, and ovarian cancers.
  • Analysis of reported oncologic outcomes (recurrence, survival) and fertility outcomes (pregnancy rates, live births).
  • Evaluation of patient selection criteria and surgical techniques employed in fertility-sparing management.

Main Results:

  • Fertility-sparing procedures can achieve favorable oncologic control in carefully selected patients.
  • Successful pregnancies and live births have been reported following various fertility-sparing interventions.
  • The risk of recurrence is generally low but requires meticulous follow-up.

Conclusions:

  • Fertility-sparing surgery is a viable option for young women with early-stage gynecologic cancers desiring future childbearing.
  • Careful patient selection and multidisciplinary management are crucial for optimizing outcomes.
  • Continued research is needed to refine techniques and expand eligibility for these life-altering procedures.