Related Experiment Video
Updated: May 31, 2026
08:47
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Rhinitis phenotypes correlate with different symptom presentation and risk factor patterns of asthma
Jonas Eriksson1, Anders Bjerg, Jan Lötvall
1Krefting Research Centre, Department of Internal Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. jonas.eriksson@lungall.gu.se
Respiratory Medicine
|July 19, 2011
Summary
Asthma and nasal comorbidities like allergic rhinitis and chronic rhinosinusitis frequently coexist. These conditions are linked to distinct asthma symptom patterns and risk factors, suggesting different asthma phenotypes.
Area of Science:
- Respiratory Medicine
- Clinical Immunology
- Epidemiology
Background:
- Asthma and rhinitis commonly occur together.
- Previous population studies have not fully explored the link between nasal conditions and asthma characteristics.
Purpose of the Study:
- To investigate the relationship between nasal comorbidities (allergic rhinitis, chronic rhinitis, chronic rhinosinusitis) and the expression of asthma symptoms.
- To determine if different nasal comorbidities are associated with unique risk factor profiles in asthma patients.
Main Methods:
- A postal questionnaire on respiratory health was distributed to 30,000 randomly selected adults (aged 16-75) in West Sweden.
- Data from 18,087 respondents were analyzed to assess the prevalence of asthma, rhinitis, chronic rhinosinusitis, and related symptoms and risk factors.
Main Results:
- High prevalence of allergic rhinitis (63.9%) and chronic rhinosinusitis (8.4%) was found in asthma patients.
- Asthma patients with chronic rhinitis or chronic rhinosinusitis reported more severe asthma and bronchitis symptoms.
- Environmental and occupational exposures were more strongly associated with asthma in the presence of chronic rhinosinusitis compared to allergic rhinitis.
Conclusions:
- A significant overlap exists between asthma and nasal comorbidities, confirming a strong association.
- Different nasal conditions are linked to distinct patterns of asthma symptoms and risk factors.
- Nasal comorbidities may serve as indicators for specific asthma phenotypes.
Related Concept Videos
01:13Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
01:28Asthma I: Introduction
Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
01:29Asthma-I: Introduction
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
01:24Asthma-III: Symptoms and Complications
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
01:26Asthma-II: Pathophysiology and Classification
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:20Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.