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Related Experiment Video

Updated: May 31, 2026

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
08:05

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

Published on: November 8, 2019

Rat tail revascularization model for advanced microsurgery training and research.

Tamer Sakrak1, A Aydan Köse, Yakup Karabağli

  • 1Department of Plastic, Reconstructive and Aesthetic Surgery, Eskişehir Osmangazi University Medical School, Eskişehir, Turkey.

Journal of Reconstructive Microsurgery
|July 19, 2011
PubMed
Summary

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This study simplified rat tail replantation for microsurgery training. Revascularization after devascularization prevented necrosis, highlighting its value for surgical skill development.

Area of Science:

  • Microsurgery
  • Surgical Training
  • Vascular Surgery

Background:

  • Microsurgical training requires effective and time-efficient models.
  • Existing models may involve complex procedures, limiting accessibility for continuous practice.

Purpose of the Study:

  • To describe a simplified microsurgical exercise for microsurgical training and research.
  • To evaluate a modified rat tail replantation model excluding bone detachment.

Main Methods:

  • A rat tail model was developed, with tails devascularized by vessel ligation.
  • Two groups were established: devascularization only (N=3) and revascularization after devascularization (N=7).
  • Circulation was monitored for one week, with reexploration for complications.

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Related Experiment Videos

Last Updated: May 31, 2026

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
08:05

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

Published on: November 8, 2019

Step By Step: Microsurgical training method combining two nonliving animal models
05:25

Step By Step: Microsurgical training method combining two nonliving animal models

Published on: May 9, 2015

In situ Transverse Rectus Abdominis Myocutaneous Flap: A Rat Model of Myocutaneous Ischemia Reperfusion Injury
11:12

In situ Transverse Rectus Abdominis Myocutaneous Flap: A Rat Model of Myocutaneous Ischemia Reperfusion Injury

Published on: June 8, 2013

Main Results:

  • Tails in the devascularization-only group showed complete necrosis.
  • In the revascularization group, only 2 out of 7 tails experienced partial necrosis.
  • Reexploration revealed thrombosis at anastomotic sites in partially necrosed tails, indicating anastomotic insufficiency.

Conclusions:

  • Total amputation is not required for effective tail devascularization in this model.
  • The simplified rat tail revascularization model is a practical tool for advanced microsurgical training.
  • This model facilitates continuing microsurgical research and skill refinement.