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Published on: May 27, 2022
Molecular diagnosis of Aspergillus fumigatus endocarditis
José C Palomares1, Samuel Bernal, María Marín
1Unidad de Gestión de Microbiología, Hospital Universitario de Valme, Ctra Cádiz s/n, Bellavista, 41014 Sevilla, Spain. jcpalomares@us.es
Abstract:
A 66-year-old male with ischaemic cardiomyopathy and chronic lymphocytic leukemia developed signs of severe systemic inflammatory response syndrome. Serial blood cultures were negative and a SeptiFast test detected the presence of Aspergillus fumigatus DNA. Afterwards, detection of galactomannan and 1,3-β-D-glucan showed a positive result. Autopsy revealed the presence of branched fungal structures suggestive of Aspergillus.
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