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Updated: May 30, 2026
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A Reference Broth Microdilution Method for Dalbavancin In Vitro Susceptibility Testing of Bacteria that Grow Aerobically
Published on: September 9, 2015
Reproducibility of broth microdilution and comparison to agar dilution for testing CB-183,315 against clinical
Diane M Citron1, Ellie J C Goldstein
1R.M. Alden Research Lab, Culver City, CA 90230, USA. d.m.citron@att.net
Diagnostic Microbiology and Infectious Disease
|July 20, 2011
Abstract:
This study evaluated the reproducibility and agreement of broth microdilution to agar dilution (AD) for testing CB-183,315, a novel lipopeptide antibiotic for Clostridium difficile. Reproducibility was 100% within ± one 2-fold dilution for 10 strains tested; agreement was 90-95% within one 2-fold dilution with AD for 103 clinical isolates.
