DC-SIGN as a receptor for phleboviruses

Pierre-Yves Lozach1, Andreas Kühbacher, Roger Meier

  • 1Institute of Biochemistry, ETH Zurich, Schafmattstrasse 18, CH-8093 Zurich, Switzerland. lozach@bc.biol.ethz.ch

Cell Host & Microbe
|July 20, 2011
PubMed
Summary

Arthropod-borne phleboviruses use the DC-SIGN receptor on dendritic cells (DCs) to enter cells. This interaction is crucial for virus infection and provides a new target for antiviral strategies.

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