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Synthesis and benzodiazepine receptor binding of 5H-pyrido[2,1-C][1,4]benzothiazines
G Trapani1, A Latrofa, M Franco
1Dipartimento Farmaco-Chimico, Facoltà di Farmacia, Università degli Studi di Bari, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|June 1, 1990
Abstract:
The pyrido[2,1-c][1,4]benzothiazines 1a-t and the pyrido[2,1-c][1,4]thiazines 7a,b were prepared and tested for their ability to displace specific [3H]diazepam binding from rat brain membranes. Some of the examined compounds of type 1 and 7b showed moderate binding affinity for the benzodiazepine receptor.