Related Experiment Video
Updated: May 30, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
A probable cluster headache case from a textbook of 1726: Francisco Suarez de Rivera's description
Background:
Few descriptions of cluster and cluster-like headache made before the 19th century have been reported.
Case Description:
We present a previously unreported early description of a probable cluster headache case made by Francisco Suárez de Rivera (1686-c.1751), one of the main physicians of the Spanish Age of Enlightenment, writer of almost 40 textbooks about medicine, surgery, pharmacology, and therapeutics.
Discussion:
The depiction here reported of a woman with probable cluster headache is possibly one of the earliest known and, to our knowledge, the first in Hispanic literature. We also review other descriptions of cluster and cluster-like headache from the same time period.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Glaucoma: Overview
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Brain Abscess l: Introduction

